To meet the needs of the growing school-age population of the City of San Pablo and its neighboring towns, a group of pioneering men, among them were Major Ricardo Bonilla, Dr. Antonio Azores, Mr. Ambrosio Alcantara and many others founded and established the San Pablo Colleges in 1947. From its humble beginnings, in makeshift rooms and in rented buildings, the San Pablo Colleges in a brief span of five years acquired a one-half hectare piece of walled lot at Hermanos Belen Street in the heart of the city of San Pablo. Dr. Antonio Azores was its first President. During Dr. Alip's tenure that full government recognition was granted to the Grade School, the Secondary School and the courses in Secretarial, Education, Commerce, Liberal Arts and Law. 

However, it was in the middle 50's that the San Pablo Colleges began to build its prestige in becoming one of the notable institutions in the country. This time a comprehensive building program was undertaken. Judge Paulo de Gala Macasaet, considered as the father of this Golden Era of Renaissance, was Chairman of the Board of Trustees and later College President. It was also during his time that the Graduate Institute was recognized and much later the Nursing Course. The objective then was a school that would be second to none. 

This quest for educational excellence initiated by Judge Macasaet is now the very goal pursued by his successors. The present leadership has embarked on programs seeking the accreditation of its courses and has been continuously searching how the teaching learning process will not only be effective and efficient but relevant as well. 

As everyone knows education is ever growing and there is no end to its progress. Every generation shall have its contribution and for now there is no substitute for the development of the College we all love and revere.